Veterinary Clinical Reference
Look up any drug or condition.
Evergreen, evidence-based hubs on the drugs, conditions, and species you manage — continuously updated and cited at every claim.
Paroxetine in Dogs and Cats
A DVM reference on extralabel paroxetine for canine and feline anxiety, aggression, and urine marking: verified dosing, onset, adverse effects, drug interactions, and how it compares with fluoxetine.
Read →Amitriptyline in Dogs and Cats: Extralabel Behavioral Pharmacology, Dosing, and Evidence
A DVM-facing clinical reference on extralabel amitriptyline in dogs and cats: TCA mechanism, canine and feline dosing, adverse effects, serotonin syndrome interactions, monitoring, and the mixed feline idiopathic cystitis evidence.
Read →Sertraline (Zoloft) in Dogs and Cats for Behavior
Sertraline is an off-label SSRI used as a maintenance adjunct to behavior modification for anxiety, aggression, and compulsive disorders in dogs and cats. This clinical hub covers extralabel dosing, 4-6 week onset, adverse effects, and the load-bearing serotonin-syndrome interaction with MAO inhibitors.
Read →Clomipramine (Clomicalm) for Dogs and Cats: Behavioral Dosing, Efficacy, and Safety
Clomipramine is a tricyclic antidepressant FDA-approved (Clomicalm) as an adjunct to behavior modification for canine separation anxiety, and used off-label for feline urine marking and canine/feline compulsive disorders. This hub covers species-specific dosing, the registration and compulsive-disorder RCTs, adverse effects, MAOI/serotonergic interactions, and where it sits versus fluoxetine, trazodone, and buspirone.
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