Veterinary Clinical Reference
Look up any drug or condition.
Evergreen, evidence-based hubs on the drugs, conditions, and species you manage — continuously updated and cited at every claim.
Canine Acute Vision Loss: Localization and Diagnostic Workup
A localization-first approach to acute canine blindness, separating opaque media, retinal dysfunction, optic-nerve disease, and central visual pathway lesions.
Read →Canine Petechiae and Ecchymoses: Hemostasis Workup
A phenotype-first diagnostic approach to canine petechiae and ecchymoses, separating platelet quantity, platelet function, coagulation-factor, DIC, and vascular causes.
Read →Canine Melena: Localization and Gastrointestinal Bleeding Workup
A clinician-facing approach to confirming melena, stabilizing significant blood loss, identifying medication and coagulopathy risks, and selecting imaging or endoscopy.
Read →Canine Paw Knuckling and Proprioceptive Deficits: Diagnostic Workup
A clinician-facing approach to distinguishing true proprioceptive dysfunction from lameness, weakness, pain, and mechanical paw placement abnormalities in dogs.
Read →Canine Allergic Skin Disease: Diagnostic Workup and Long-Term Planning
A clinician-facing framework for the pruritic dog: minimum dermatologic database, infection and ectoparasite control, diet-trial interpretation, atopy assessment, and longitudinal outcomes.
Read →Salt Toxicosis and Hypernatraemia in Dogs: A Clinical Reference
Salt toxicosis kills through correction, not concentration. Exposure sources, the sodium thresholds that matter, free water deficit, and the maximum safe correction rate for acute versus chronic hypernatraemia in dogs.
Read →Lead Toxicosis in Dogs: Diagnosis and Chelation Therapy
An ER/toxicology reference for lead poisoning in dogs (cats noted): sources, the combined GI-neurologic presentation, basophilic stippling and nRBCs, whole-blood lead thresholds, radiography, and the stabilize-remove GI lead-chelate sequence with exact CaEDTA, succimer, and D-penicillamine doses.
Read →Zinc Toxicosis in Dogs: Sources, Hemolysis, Diagnosis, and Treatment
Canine zinc toxicosis causes intravascular hemolysis, hemoglobinuria, and multi-organ injury, usually from a swallowed post-1982 penny or galvanized metal. A clinical reference on zinc sources, the royal-blue-top tube pitfall, source removal, and the chelation debate.
Read →Selegiline (Anipryl / L-deprenyl) for Canine Cognitive Dysfunction
A DVM clinical reference on selegiline (Anipryl) for canine cognitive dysfunction syndrome: the labeled 0.5–1.0 mg/kg PO q24h dose, MAO-B mechanism, realistic open-label efficacy, adverse effects, and the load-bearing serotonin-syndrome interactions with SSRIs, TCAs, trazodone, tramadol, and amitraz.
Read →Sileo (Dexmedetomidine Oromucosal Gel) for Canine Noise Aversion: Dosing, Efficacy, and Safety
Sileo (dexmedetomidine oromucosal gel) is the first and only FDA-approved treatment for canine noise aversion — an alpha-2 agonist absorbed transmucosally, dosed by weight as syringe "dots" and given shortly before or at the onset of an anticipated noise event. This hub covers label dosing, the pivotal RCT, adverse effects, contraindications, and where it sits against trazodone, clonidine, tasipimidine, and daily SSRIs.
Read →Clonidine for Dogs: Off-Label Alpha-2 Agonist for Noise Aversion, Storm Phobia, and Situational Anxiety
Clonidine is a human alpha-2 adrenergic agonist used off-label in dogs as a short-acting, event-based adjunct for situational fear and anxiety — noise aversion, storm phobia, separation-related distress, fear reactivity, and vet-visit anxiety — layered on a daily SSRI or TCA plus behavior modification rather than run as standalone monotherapy. This hub summarizes the off-label dosing (~0.01–0.05 mg/kg PO), the limited open-label efficacy evidence, adverse effects, contraindications and interactions, and where clonidine sits relative to the FDA-approved event drug dexmedetomidine oromucosal gel (Sileo), trazodone, and gabapentin.
Read →Trazodone for Dogs: Situational Anxiety and Post-Op Confinement Dosing
A clinical reference for prescribing trazodone in dogs: SARI mechanism, off-label status, situational and post-operative confinement dosing, onset, adverse effects, and serotonin syndrome risk with concurrent SSRIs and MAOIs.
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